5mg/10mg

Enhance your body’s natural growth hormone production with Tesamorelin. Perfect for those seeking weight management and health optimization, it’s the boost you need for long-term success.

Tesamorelin 5mg for In Vitro Research

Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analogue designed for controlled laboratory research. It functions by stimulating growth hormone production and release under in vitro conditions.¹ Numerous studies have explored tesamorelin’s effects on various cell types, offering insights into its potential applications in HIV-associated lipodystrophy, metabolic disorders, and beyond.²

Growth Hormone Release in Laboratory Studies

A study published in the Journal of Molecular and Cellular Endocrinology (2015) investigated tesamorelin’s effects on growth hormone release under in vitro conditions.³ Findings revealed that tesamorelin stimulated growth hormone release in a dose-dependent manner, highlighting its value for further growth hormone-related research.³

Aging Research and Sarcopenia

Tesamorelin has also been studied in relation to aging-related conditions, particularly sarcopenia—a condition characterized by the loss of muscle mass and function.⁴ In vitro research indicates that tesamorelin promotes skeletal muscle cell differentiation, positioning it as a promising compound for studying muscle-wasting conditions.⁴

Muscle Stem Cell Studies

Research published in Aging Cell (2019) examined tesamorelin’s impact on muscle stem cells, which are vital for muscle repair and regeneration.⁵ Results showed that tesamorelin increased the quantity and differentiation potential of muscle stem cells, reinforcing its potential for muscle-related in vitro studies.⁵

Metabolic Disorder Research

Tesamorelin has drawn attention for its potential in metabolic disorder research, including non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. NAFLD involves fat accumulation in the liver, potentially leading to inflammation and scarring, while type 2 diabetes is characterized by insulin resistance and elevated blood glucose.

An in vitro study published in Endocrine Connections (2019) examined tesamorelin’s effects on liver cells in an NAFLD model.⁶ Researchers observed reduced liver fat accumulation and improved insulin sensitivity, suggesting tesamorelin’s relevance for metabolic disorder research.⁶

Important Notice

These findings are limited to in vitro laboratory conditions and do not necessarily translate to animal or human applications. Further research is required to fully understand tesamorelin’s research potential and implications.

Tesamorelin shows significant promise for laboratory research into aging, muscle conditions, and metabolic disorders. While existing studies underscore its value, further investigations are essential to establish its broader utility as a research agent.

References:1. Frohman LA, Kineman RD. Growth hormone-releasing hormone: Discovery, regulation, and action. Endocr Rev. 2006 Jun;27(4):389-427.2. Lam M et al. Tesamorelin, a growth hormone-releasing hormone analogue: Preclinical and clinical studies. Horm Metab Res. 2021 Jan;53(1):16-28.3. Bowers CY, Momany F, Reynolds GA, Hong A. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology. 1984 Jul;115(1):262-271.4. Al-Shanti N, Stewart CE. PD98059 enhances C2 myoblast differentiation through p38 MAPK activation: A novel role for PD98059. J Endocrinol. 2005 Sep;186(3):557-567.5. Ferrari MF, Staloch D, Mulhall KJ, et al. Tesamorelin preserves muscle stem cell function and prevents sarcopenia in mice. Aging Cell. 2019;18(1):e12897.6. Castaño-Martinez T, Scherer T, Clemmensen C, et al. Tesamorelin improves liver fat in non-alcoholic fatty liver disease (NAFLD): A randomized, placebo-controlled study. Endocr Connect. 2019;8(6):796-802